Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548973 | 0.87 | RIPK1 (0.53) | RIPK1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL10544009 | 0.84 | ALDH1A1 (0.42) | RIPK1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL10549648 | 0.83 | PDK1 (0.45) | ALDH1A1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL10546564 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10547048 | 0.78 | TP53 (0.48) | RIPK1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6182681 | 0.75 | KMT2A (0.69) | RIPK1ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10548744 | 0.75 | MLYCD (0.48) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2634610 | 0.74 | RIPK1 (0.64) | RIPK1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL662742 | 0.74 | RIPK1 (0.64) | RIPK1ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL10546095 | 0.74 | KMT2A (0.44) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |