Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894633 | 0.85 | KEAP1 (0.55) | DHODHCSNK2A1CSNK2A2CSNK2BXDH | |
| SCHEMBL10550275 | 0.84 | L3MBTL1 (0.44) | DHODHCSNK2A1CSNK2A2CSNK2BCDK2 | |
| SCHEMBL10757185 | 0.82 | CSNK2A1 (0.47) | DHODHCSNK2A1MEN1KMT2AMAPT | |
| SCHEMBL10547323 | 0.77 | LMNA (0.44) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL15638933 | 0.77 | DHODH (0.64) | DHODHCSNK2A1CSNK2A2CSNK2BXDH | |
| SCHEMBL24279936 | 0.77 | KEAP1 (0.55) | DHODHCSNK2A1CSNK2A2CSNK2BXDH | |
| SCHEMBL10469514 | 0.76 | KEAP1 (0.44) | DHODHMAPK8AURKAMAPTALDH1A1 | |
| SCHEMBL6801722 | 0.74 | CTSV (0.60) | DHODHXDHSLC22A12GSK3BCDC7 | |
| SCHEMBL10169403 | 0.72 | SYK (0.44) | DHODHMAPTALDH1A1TP53 | |
| SCHEMBL894667 | 0.72 | MAPK9 (0.47) | DHODHCSNK2A1CSNK2A2CSNK2BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851535-A | 2-(5-FLUORONICOTINOYL)ACETIC ACID DERIVATIVES, ANTIBACTERIAL 1-ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINES | TOYAMA CHEMICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4704459-A | VILSMEIER REAGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-11-03 | — | — | US | disclosed |