Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550257 | 0.84 | DHODH (0.55) | MAPTMEN1KMT2ADHODHABCC1 | |
| SCHEMBL10546863 | 0.84 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL10468704 | 0.79 | CA12 (0.39) | L3MBTL1NPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL10547323 | 0.79 | LMNA (0.44) | RAB9ACASP3SMN1; SMN2SENP7MAPT | |
| SCHEMBL10467030 | 0.75 | PGK1 (0.38) | L3MBTL1NPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL8751819 | 0.75 | CA12 (0.43) | L3MBTL1NPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL8834288 | 0.74 | MAPT (0.51) | L3MBTL1NPC1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL10468563 | 0.73 | ROCK2 (0.54) | CDK2HPGDALDH1A1 | |
| SCHEMBL15636015 | 0.73 | DHODH (0.72) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10469441 | 0.73 | CHRNA7 (0.40) | L3MBTL1SMN1; SMN2MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851535-A | 2-(5-FLUORONICOTINOYL)ACETIC ACID DERIVATIVES, ANTIBACTERIAL 1-ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINES | TOYAMA CHEMICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4704459-A | VILSMEIER REAGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-11-03 | — | — | US | disclosed |