Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | BBOX1 | O75936 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL105516 | 0.88 | LMNA (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Levulinic Acid SCHEMBL357248 | 0.88 | ALDH1A1 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Adipic Acid SCHEMBL106656 | 0.87 | BBOX1 (0.58) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Glutarate SCHEMBL104188 | 0.87 | BBOX1 (0.58) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL18166887 | 0.85 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Sebacic Acid SCHEMBL5874500 | 0.84 | BBOX1 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Tetramethylammonium Ion SCHEMBL8438225 | 0.84 | BBOX1 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Adipic Acid SCHEMBL8028995 | 0.84 | BBOX1 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL109152 | 0.84 | FFAR3 (0.82) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28871070 | 0.81 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2026-03-12 | — | — | US | claimed |
| EP-4323425-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | Novomer, Inc. (US) | 2024-02-21 | — | — | EP | claimed |
| CN-117157342-A | Polypropylene lactone and preparation method | 诺沃梅尔公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2022221266-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER, INC. (US) | 2022-10-20 | — | — | WO | claimed |
| US-10246558-B2 | Compositions comprising siloxane compounds and methods for using the same | MILLIKEN & COMPANY (US) | 2019-04-02 | — | — | US | claimed |
| EP-3458498-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | Milliken & Company (US) | 2019-03-27 | — | — | EP | claimed |
| WO-2017201035-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | MILLIKEN & COMPANY (US) | 2017-11-23 | — | — | WO | claimed |
| US-20170335065-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | MILLIKEN & COMPANY | 2017-11-23 | — | — | US | claimed |
| US-5393386-A | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-28 | — | — | US | claimed |
| JP-6248065-A | — | — | None | — | — | JP | disclosed |
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-12338318-B2 | Polypropiolactones and methods of preparation | NOVOMER, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20240228695-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOVOMER INC (US) | 2024-07-11 | — | — | US | disclosed |
| EP-4323425-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | Novomer, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| EP-0608545-B1 | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0708452-A1 | Ion-conductive polymer electrolyte, method for producing the electrolyte and capacitors using the electrolyte | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5393386-A | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| JP-H06248065-A | POLYMERIZATION INITIATOR FOR 2-OXETANONE AND PRODUCTION OF POLY(2-OXETANONE) | TOKUYAMA SODA CO LTD | 1994-09-06 | — | — | JP | disclosed |
| EP-0608545-A1 | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-4915861-A | DICARBOXYLIC ACID SALT OF TETRAMETHYLAMMONIUM | NIPPON CHEMI-CON CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071024-A1 | POLYPROPIOLACTONES AND METHODS OF PREPARATION | NOTUM, ALKBH3, EBP | FFAR3 177/4885HDAC3 1967/4885HDAC1 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.