Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052080 | 0.74 | CA12 (0.59) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL9807889 | 0.74 | CA12 (0.39) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL31037170 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL18938478 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL29967380 | 0.73 | BRPF1 (1.00) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1054493 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1055461 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL271495 | 0.73 | CA12 (0.63) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL487525 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL29313185 | 0.73 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072509-A1 | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-24 | — | — | EP | claimed |
| JP-54151985-A | — | — | None | — | — | JP | disclosed |
| US-20170368060-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9783512-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-9783512-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160075668-A1 | BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-03-17 | — | — | US | disclosed |
| US-9221842-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221842-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-9115151-B2 | Substituted 2,10-dihydro-9-oxa-1,2,4A-triazaphenanthren-3-ones and uses thereof | ABBVIE INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-20140206663-A1 | TRIAZINONE COMPOUNDS | WUXI APPTECH (SHANGHAI) CO., LTD. (CN) | 2014-07-24 | — | — | US | disclosed |
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0311634-A4 | 6-(6-ALKYLPYRIDONE)-CARBOSTYRIL COMPOUNDS AND THEIR CARDIOTONIC USES. | RORER INTERNAT OVERSEAS INC (US) | 1989-06-26 | — | — | EP | disclosed |
| EP-0311634-A1 | 6-(6-ALKYLPYRIDONE)-CARBOSTYRIL COMPOUNDS AND THEIR CARDIOTONIC USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4785005-A | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses | RORER PHARMACEUTICAL CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| WO-1988000188-A1 | 6-(6-ALKYLPYRIDONE)-CARBOSTYRIL COMPOUNDS AND THEIR CARDIOTONIC USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-01-14 | — | — | WO | disclosed |
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| JP-S54151985-A | PREPARATION OF AMINOCARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1979-11-29 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368060-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | GRIN2C, TPH1, HTR2C | CA12 4505/4885CA9 4837/4885BRD4 47/4885 |
| US-20140206663-A1 | TRIAZINONE COMPOUNDS | THPO, IL5, CYP11B2 | CA12 3540/4885CA9 2939/4885BRD4 1157/4885 |
| US-20160075668-A1 | BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF | AAAS, CYCS, AOC2 | CA12 3317/4885CA9 965/4885BRD4 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.