Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554712 | 0.77 | MAPT (0.42) | RAB9AGAAMAPTMAPK1 | |
| SCHEMBL10547817 | 0.76 | MAPT (0.40) | KDM4ESMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10549444 | 0.76 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL13439673 | 0.63 | HCAR3 (0.51) | RAB9AKDM4EGRM5HCAR3AURKA | |
| SCHEMBL5651799 | 0.61 | LIPE (0.69) | RAB9AKDM4EHIF1AEPAS1LIPE | |
| SCHEMBL18112755 | 0.61 | OPRM1 (0.43) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL28056230 | 0.60 | HCAR3 (0.51) | RAB9AKDM4EGRM5HCAR3AURKA | |
| SCHEMBL17114620 | 0.60 | NPC1 (0.63) | RAB9AKDM4EHCAR3AURKALIPE | |
| SCHEMBL17028079 | 0.60 | ALDH1A1 (0.56) | RAB9AKDM4EHIF1ASMN1; SMN2MAPT | |
| SCHEMBL17403557 | 0.60 | GSK3B (0.52) | KDM4EHIF1AEPAS1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847251-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |