Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918255 | 0.82 | ACHE (0.40) | ACHEL3MBTL1MAPK1DPP4SMN1; SMN2 | |
| SCHEMBL15034187 | 0.82 | DPP4 (0.45) | ACHEMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL13936206 | 0.81 | ACHE (0.43) | ACHEMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL23704445 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1MEN1POLBALOX12 | |
| SCHEMBL30164264 | 0.75 | NOS3 (0.46) | L3MBTL1MAPK1KMT2ARAB9ACYP1A2 | |
| SCHEMBL286660 | 0.75 | NOS3 (0.46) | L3MBTL1MAPK1KMT2ARAB9ACYP1A2 | |
| SCHEMBL13928210 | 0.74 | CHRNB2 (0.43) | ACHEMAPTHPGDL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193387 | 0.74 | NOS3 (0.45) | L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL29861810 | 0.74 | NOS3 (0.45) | L3MBTL1CYP1A2 | |
| SCHEMBL10084727 | 0.73 | ACHE (0.46) | ACHEMAPTHPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861780-A | 4(3H)-quinazolinone derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |