Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170830 | 1.00 | TSHR (0.50) | TSHREPHX1CA12CA1CA2 | |
| SCHEMBL1051503 | 1.00 | TSHR (0.50) | TSHREPHX1CA12CA1CA2 | |
| SCHEMBL873507 | 1.00 | TSHR (0.50) | TSHREPHX1CA12CA1CA2 | |
| SCHEMBL6050318 | 0.88 | — | — | |
| SCHEMBL4626349 | 0.84 | LMNA (0.39) | TSHREPHX1LMNASMN1; SMN2 | |
| Butyric Acid SCHEMBL28983073 | 0.84 | FFAR3 (0.42) | TSHREPHX1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL8444779 | 0.82 | TSHR (0.44) | TSHREPHX1CA12CA1CA2 | |
| SCHEMBL6559706 | 0.82 | TSHR (0.50) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL9609345 | 0.82 | TSHR (0.44) | TSHREPHX1CA12CA1CA2 | |
| SCHEMBL8674655 | 0.82 | TSHR (0.44) | TSHREPHX1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8506943-B2 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-8506943-B2 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-8506943-B2 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2281581-B1 | Method of using cyclohexylethyl carboxylic acid esters for reducing malodors | INT FLAVORS & FRAGRANCES INC (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-2281581-B1 | Method of using cyclohexylethyl carboxylic acid esters for reducing malodors | INT FLAVORS & FRAGRANCES INC (US) | 2013-04-17 | — | — | EP | disclosed |
| US-20110250159-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-10-13 | — | — | US | disclosed |
| US-20110250159-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-10-13 | — | — | US | disclosed |
| US-20110250158-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-10-13 | — | — | US | disclosed |
| US-20110250158-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-10-13 | — | — | US | disclosed |
| US-20110250158-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-10-13 | — | — | US | disclosed |
| US-7993633-B2 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2281581-A1 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | International Flavors & Fragrances Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-2281581-A1 | Cyclohexylethyl carboxylic acid ester compositions and method for using the same for reducing malodors | International Flavors & Fragrances Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| US-20110014142-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-01-20 | — | — | US | disclosed |
| US-20110014142-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-01-20 | — | — | US | disclosed |
| US-20110014142-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2011-01-20 | — | — | US | disclosed |
| US-20080227978-A1 | Converting a carbonyl group within a substrate to a chiral alcohol moiety by reacting the carbonyl containing substrate with an organoaluminium reagent in the presence of a Group 5-12 transition metal based catalyst which is complexed with a chiral ligand; excellent yields | THE UNIVERSITY OF NOTTINGHAM | 2008-09-18 | — | — | US | disclosed |
| US-7156731-B2 | Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts | POSTECH FOUNDATION (KR) | 2007-01-02 | — | — | US | disclosed |
| WO-2005095629-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED ESTERS AND ALCOHOLS BY MEANS OF AZEOTROPICALLY DRIED ENZYME COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2005-10-13 | — | — | WO | disclosed |
| US-20050130282-A1 | Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014142-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | ME1, BCHE, PCCA | TSHR 2873/4885EPHX1 251/4885CA12 1998/4885 |
| US-20110250158-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | ME1, BCHE, PCCA | TSHR 2873/4885EPHX1 251/4885CA12 1998/4885 |
| US-20080227978-A1 | Converting a carbonyl group within a substrate to a chiral alcohol moiety by reacting the carbonyl containing substrate with an organoaluminium reagent in the presence of a Group 5-12 transition metal based catalyst which is complexed with a chiral ligand; excellent yields | ADH5, ADH1C, CYP2E1 | TSHR 3877/4885EPHX1 2421/4885CA12 101/4885 |
| US-20110250159-A1 | CYCLOHEXYLETHYL CARBOXYLIC ACID ESTER COMPOSITIONS AND METHOD FOR USING THE SAME FOR REDUCING MALODORS | ME1, BCHE, PCCA | TSHR 2873/4885EPHX1 251/4885CA12 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.