Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558739 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| SCHEMBL10353455 | 0.80 | HDAC3 (0.49) | ALDH1A1HSD17B10LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10554781 | 0.77 | ALOX5 (0.51) | ALDH1A1LMNA | |
| SCHEMBL7320071 | 0.77 | KMT2A (0.55) | KMT2AALDH1A1MEN1POLBLMNA | |
| SCHEMBL10558367 | 0.75 | EIF2AK2 (0.42) | KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7325551 | 0.74 | LMNA (0.53) | CA12CA1CA9HSD17B10LMNA | |
| SCHEMBL8775491 | 0.74 | CHRM2 (0.53) | KMT2AALDH1A1MEN1LMNAHPGD | |
| SCHEMBL135357 | 0.73 | PGR (0.52) | KMT2AALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL8823315 | 0.73 | PGR (0.52) | KMT2AALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL458085 | 0.73 | CA12 (1.00) | CA12CA1CA9KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816454-A | CARDIOVASCULAR DISORDERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |