SCHEMBL32667382

SCHEMBL32667382

COc1ccc2c(=O)c(-c3cccc(CCCCCCCCCCBr)c3)coc2c1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 3/20 0.46
▸ MAPT P10636 6/20 0.41
▸ ALDH1A1 P00352 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ TP53 P04637 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CYP3A4 P08684 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ BCHE P06276 1/20 0.40
▸ NPC1 O15118 3/20 0.39
▸ RAB9A P51151 3/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ ALOX12 P18054 2/20 0.39
▸ PIK3CA P42336 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ PPARG P37231 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27074007 0.90 ACHE (0.44) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL27039791 0.87 MAPT (0.50) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL27074024 0.79 MAPT (0.53) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL10563531 0.77 MAPT (0.48) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL571684 0.77 MAPT (0.54) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL4680788 0.77 ALDH1A1 (0.57) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL28730377 0.76 MAPT (0.63) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL29550916 0.76 MAPT (0.63) ACHEMAPTALDH1A1MEN1KMT2A
SCHEMBL27039653 0.76 ALOX15 (0.47) MAPTALDH1A1MEN1KMT2ATP53
SCHEMBL27074023 0.73 MAPT (0.57) ACHEMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028364-A1 CATIONIC CHROMENONES AND THEIR USE IN ONCOLOGY FLORATEK PHARMA S A (CH) 2026-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028364-A1 CATIONIC CHROMENONES AND THEIR USE IN ONCOLOGY NR3C2, MC2R, NR3C1 ACHE 4638/4885MAPT 4264/4885ALDH1A1 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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