SCHEMBL10567172

SCHEMBL10567172

Brc1c(-c2ccccc2)sc(-c2ccccc2)c1Br

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
MAPK1 P28482 2/20 0.46
PTPN1 P18031 2/20 0.43
PTPRC P08575 1/20 0.43
PTPN2 P17706 1/20 0.43
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
MAPT P10636 2/20 0.40
ALOX5 P09917 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
TDO2 P48775 1/20 0.37
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
GRM6 O15303 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23232540 0.85 MAPT (0.41) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL14832250 0.84 GRM6 (0.44) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL10567364 0.79 ALDH1A1 (0.42) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL6437003 0.77 GPR3 (0.46) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL2150616 0.77 PTPN1 (0.37) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL1224397 0.74 MAPT (0.56) ALDH1A1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL6238908 0.74 ALDH1A1 (0.44) ALDH1A1MAPK1CYP1A2CYP2D6CYP2C19
SCHEMBL10570016 0.74 ALDH1A1 (0.38) ALDH1A1MAPK1PTPN1PTPRCPTPN2
SCHEMBL24817276 0.74 ALDH1A1 (0.58) ALDH1A1MAPK1PTPRCCYP1A2CYP2D6
SCHEMBL2393906 0.74 ALDH1A1 (0.58) ALDH1A1MAPK1PTPRCCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271283-A Synthesis method of 9, 10-dithio (hetero) phenanthrene 中南大学 2024-07-02 CN disclosed
WO-2022101171-A1 SULFUROUS COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-05-19 WO disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-4820827-A 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-11 US disclosed
US-4590205-A Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-20 US disclosed
EP-0087629-B1 ANTIINFLAMMATORY AND/OR ANALGESIC 2,3-DIARYL-5-HALO THIOPHENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-15 EP disclosed
EP-0087629-A2 Antiinflammatory and/or analgesic 2,3-Diaryl-5-halo thiophenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-09-07 EP disclosed