Sugi Predict

Sugi Predict / Compounds / SCHEMBL10567265

SCHEMBL10567265

SCHEMBL10567265

COc1cc([N+](=O)[O-])c(F)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.47
▸ MAPT P10636 4/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ PRKDC P78527 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ TDP1 Q9NUW8 2/20 0.44
▸ GAA P10253 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ ATM Q13315 1/20 0.42
▸ ESPL1 Q14674 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ PKM P14618 2/20 0.40
▸ TTR P02766 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934878 0.93 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL4306952 0.93 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL3273374 0.86 MAPT (0.47) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL31377991 0.85 ALDH1A1 (0.58) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL1766175 0.85 ALDH1A1 (0.58) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL512256 0.84 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL5424277 0.84 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL29804996 0.84 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL29975509 0.84 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ECYP3A4ALOX15
SCHEMBL25379066 0.83 PTGES (0.38) ALDH1A1MAPTKDM4ECYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260047267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-12 — — US disclosed
EP-4683909-A2 ATM KINASE INHIBITORS Eberhard Karls Universität Tübingen (DE) 2026-01-28 — — EP disclosed
US-20260015328-A1 ATM KINASE INHIBITORS EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2026-01-15 — — US disclosed
US-20250212677-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-06-26 — — US disclosed
CN-120157715-A Organic electroluminescent material and device 环球展览公司 2025-06-17 — — CN disclosed
EP-4524139-A1 IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE Shanghai Simr Biotechnology Co., Ltd. (CN) 2025-03-19 — — EP disclosed
WO-2025037871-A1 TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR 에스케이바이오팜 주식회사 2025-02-20 — — WO disclosed
WO-2024194460-A2 ATM KINASE INHIBITORS EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2024-09-26 — — WO disclosed
EP-4434972-A1 ATM KINASE INHIBITORS Eberhard-Karls-Universität Tübingen (DE) 2024-09-25 — — EP disclosed
US-20240043420-A1 7-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN INC. 2024-02-08 — — US disclosed
EP-2970200-A1 PYRIDINE CDK9 KINASE INHIBITORS Abbvie Inc. (US) 2016-01-20 — — EP disclosed
WO-2015115673-A1 FUSED IMIDAZOLE COMPOUNDS ONO PHARMACEUTICAL CO., LTD. (JP) 2015-08-06 — — WO disclosed
WO-2015006100-A1 ARYL AMIDE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-01-15 — — WO disclosed
WO-2015006100-A1 ARYL AMIDE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-01-15 — — WO disclosed
WO-2014160017-A1 PYRIDINE CDK9 KINASE INHIBITORS ABBVIE INC. (US) 2014-10-02 — — WO disclosed
US-20140275011-A1 PYRIDINE CDK9 KINASE INHIBITORS ABBVIE INC. (US) 2014-09-18 — — US disclosed
US-4818276-A Herbicidal 1-aryl-Δ2 -1,2,4-triazolin-5-ones FMC CORPORATION (US) 1989-04-04 — — US disclosed
EP-0231176-A1 HERBICIDAL 1-ARYL-$g(d)?2 -1,2,4-TRIAZOLIN-5-ONES FMC Corporation (US) 1987-08-12 — — EP disclosed
WO-1987000730-A1 HERBICIDAL 1-ARYL-delta2-1,2,4-TRIAZOLIN-5-ONES FMC CORPORATION (US) 1987-02-12 — — WO disclosed
CN-85106905-A Contain 1-aryl-Δ 2-1,2,4, weedicide of-triazoline-5-ketone and preparation method thereof — 1987-02-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240043420-A1 7-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ABL1, ABL2, BCR ALDH1A1 1355/4885MAPT 4135/4885KDM4E 476/4885
US-20140275011-A1 PYRIDINE CDK9 KINASE INHIBITORS CDK9, CDK19, CDK6 ALDH1A1 3595/4885MAPT 2993/4885KDM4E 340/4885
US-20260015328-A1 ATM KINASE INHIBITORS ATM, CHEK2, CHEK1 ALDH1A1 4484/4885MAPT 1465/4885KDM4E 2112/4885
US-20250212677-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, LOXL1, OCIAD1 ALDH1A1 815/4885MAPT 2647/4885KDM4E 2873/4885
US-20260047267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, NPY1R ALDH1A1 2125/4885MAPT 3928/4885KDM4E 3898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.