Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569629 | 0.90 | HTR7 (0.45) | HTR7GAAALOX15MEN1KMT2A | |
| SCHEMBL10571671 | 0.81 | AADAT (0.40) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10569235 | 0.75 | ALDH1A1 (0.51) | GAAALOX15ALDH1A1MAPTAADAT | |
| SCHEMBL10568846 | 0.75 | AADAT (0.39) | GAAALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL10568989 | 0.75 | MEN1 (0.43) | HTR7GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10570255 | 0.75 | MEN1 (0.52) | HTR7MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL10568945 | 0.75 | ALDH1A1 (0.51) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10565374 | 0.75 | ALDH1A1 (0.55) | GAAALOX15MEN1KMT2AALDH1A1 | |
| SCHEMBL10570196 | 0.74 | MAPT (0.44) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL10569729 | 0.74 | KMT2A (0.46) | GAAALOX15MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |