Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569171 | 0.82 | HTR1A (0.40) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7932619 | 0.81 | LMNA (0.45) | KMT2AMEN1MGLLALDH1A1GAA | |
| SCHEMBL10572666 | 0.81 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL10569563 | 0.80 | MEN1 (0.52) | KMT2AMEN1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL10568846 | 0.77 | AADAT (0.39) | KMT2AMEN1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10569629 | 0.75 | HTR7 (0.45) | KMT2AMEN1ALDH1A1ALOX15GAA | |
| SCHEMBL10571688 | 0.74 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10568951 | 0.74 | HTR7 (0.44) | KMT2AMEN1ALDH1A1ALOX15GAA | |
| SCHEMBL10572100 | 0.74 | MEN1 (0.52) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10569258 | 0.72 | MGLL (0.46) | KMT2AMEN1MGLLALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |