Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.47 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.47 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.47 |
| ▸ | GGH | Q92820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605401 | 1.00 | ALDH1A1 (0.55) | ALDH1A1NAALAD2CA2HPGDCA1 | |
| Methylamine SCHEMBL10771739 | 0.97 | HPGD (0.53) | ALDH1A1NAALAD2CA2HPGDCA1 | |
| SCHEMBL4384045 | 0.90 | CA2 (0.53) | ALDH1A1CA2HPGDCA1RAB9A | |
| SCHEMBL4881536 | 0.89 | HPGD (0.57) | ALDH1A1HPGDRAB9ACTSLHDAC1 | |
| SCHEMBL9705401 | 0.83 | RAB9A (0.54) | ALDH1A1CA2HPGDCA1RAB9A | |
| SCHEMBL9705400 | 0.83 | RAB9A (0.54) | ALDH1A1CA2HPGDCA1RAB9A | |
| SCHEMBL11386076 | 0.83 | RAB9A (0.54) | ALDH1A1CA2HPGDCA1RAB9A | |
| SCHEMBL8144685 | 0.82 | HSPA5 (0.61) | ALDH1A1HPGDRAB9ACTSLGAA | |
| SCHEMBL9955478 | 0.82 | CA2 (0.55) | ALDH1A1CA2HPGDCA1RAB9A | |
| SCHEMBL11221728 | 0.82 | CA2 (0.55) | ALDH1A1CA2HPGDCA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545771-A | Application of cellular immunotherapy | 克莱格医学有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115216449-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-107090456-B | Inhibition of beta 1 gene expression using short interfering nucleic acids mediated by RNA interference of catenin (cadherin-associated protein) | 瑟纳治疗公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-113214246-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-106795151-B | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111989344-A | Methods and compositions for treating tumors | 科济生物医药（上海）有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-101801379-A | CSF-1R inhibitors for treatment of cancer and bone diseases | NOVARTIS AG | 2010-08-11 | — | — | CN | disclosed |
| US-4882334-A | ANTITUMOR AGENTS INHIBIT ENZYMES WHICH USE FOLIC ACID OR ITS METABOLITES AS SUBSTRATE; ANTICARCINOGENIC | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-21 | — | — | US | disclosed |