Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.50 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.50 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.50 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705400 | 1.00 | RAB9A (0.54) | RAB9ACTSLHDAC1HPGDCA1 | |
| SCHEMBL11386076 | 1.00 | RAB9A (0.54) | RAB9ACTSLHDAC1HPGDCA1 | |
| SCHEMBL8144685 | 0.86 | HSPA5 (0.61) | RAB9ACTSLHDAC1HPGDHSPA5 | |
| SCHEMBL10654984 | 0.84 | CTSL (0.68) | RAB9ACTSLHPGDCA1CA2 | |
| SCHEMBL10654990 | 0.84 | CTSL (0.68) | RAB9ACTSLHPGDCA1CA2 | |
| SCHEMBL10569530 | 0.83 | ALDH1A1 (0.55) | RAB9ACTSLHDAC1HPGDCA1 | |
| SCHEMBL1605401 | 0.83 | ALDH1A1 (0.55) | RAB9ACTSLHDAC1HPGDCA1 | |
| SCHEMBL4384045 | 0.82 | CA2 (0.53) | RAB9ACTSLHDAC1HPGDCA1 | |
| SCHEMBL16993875 | 0.81 | CTSL (0.57) | RAB9ACTSLHPGDCA1CA2 | |
| SCHEMBL11385542 | 0.81 | KMT2A (0.53) | RAB9ACTSLHDAC1HPGDHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770170-B2 | Methods for diagnosing, treating, and monitoring chronic inflammatory response syndrome | SHOEMAKER RITCHIE (US) | 2017-09-26 | — | — | US | disclosed |
| US-20160000837-A1 | COMPOSITIONS AND METHODS TO ALTER GUT MICROBIAL FERMENTATION USING SULFATE-REDUCING BACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| WO-1992016204-A1 | METHOD OF REDUCING SERUM LEVELS OF LIPOPROTEIN(A) | MEDICIS CORPORATION (US) | 1992-10-01 | — | — | WO | disclosed |
| US-4259508-A | MUCOLYTIC, EMOLLIENT | BLUM JEAN | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000837-A1 | COMPOSITIONS AND METHODS TO ALTER GUT MICROBIAL FERMENTATION USING SULFATE-REDUCING BACTERIA | SI, HSD17B14, MGAM | RAB9A 3066/4885CTSL 3574/4885HDAC1 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.