Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691306 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GLALMNAHTTHSD17B10 | |
| SCHEMBL9768384 | 0.78 | RAD52 (0.34) | ALDH1A1RAD52MAPTPKM | |
| SCHEMBL9768382 | 0.78 | RAD52 (0.34) | ALDH1A1RAD52MAPTPKM | |
| Hydrochloric Acid SCHEMBL10773272 | 0.74 | HIF1A (0.33) | LMNARAD52MAPT | |
| SCHEMBL9768339 | 0.73 | RAD52 (0.42) | ALDH1A1LMNAHSD17B10RAD52TSHR | |
| SCHEMBL10572167 | 0.73 | RAD52 (0.42) | ALDH1A1LMNAHSD17B10RAD52TSHR | |
| SCHEMBL10770978 | 0.72 | DRD2 (0.40) | ALDH1A1RAD52TDP1MEN1KMT2A | |
| SCHEMBL10710825 | 0.71 | KDM4E (0.40) | ALDH1A1TDP1DRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10772441 | 0.71 | LMNA (0.44) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL9830536 | 0.69 | LMNA (0.44) | ALDH1A1GLALMNAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831028-A | Novel benzothiazinone derivatives, processes for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0244723-A2 | Benzothiazinone derivatives, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-11 | — | — | EP | disclosed |
| EP-0243886-A2 | Benzothiazinone derivatives, process for their preparation, therapeutic agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | disclosed |