Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694665 | 0.83 | RAD52 (0.36) | ALDH1A1HTTLMNAHSD17B10RAD52 | |
| SCHEMBL10691597 | 0.81 | ADRA1A (0.39) | ALDH1A1RAD52TSHRTDP1MAPT | |
| SCHEMBL10696619 | 0.80 | RAD52 (0.34) | ALDH1A1HTTHSD17B10RAD52POLB | |
| SCHEMBL10569643 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GLAHTTLMNAHSD17B10 | |
| SCHEMBL10695401 | 0.74 | RAD52 (0.42) | ALDH1A1HTTLMNARAD52TSHR | |
| SCHEMBL10692789 | 0.69 | BACE1 (0.37) | ALDH1A1HTTLMNAHSD17B10TSHR | |
| SCHEMBL10691593 | 0.68 | L3MBTL1 (0.42) | ALDH1A1LMNATSHRPOLBPKM | |
| SCHEMBL10691351 | 0.67 | GPR55 (0.39) | ALDH1A1HTTLMNAHSD17B10RAD52 | |
| SCHEMBL10693674 | 0.67 | BACE1 (0.35) | ALDH1A1HTTLMNAHSD17B10TSHR | |
| SCHEMBL10339678 | 0.66 | ALDH1A1 (0.57) | ALDH1A1GLALMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |