SCHEMBL10572305

SCHEMBL10572305

COc1ccccc1C(c1ccccc1)(c1ccccc1OC)C(O)[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1O.NP(O)O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.47
RNASE1 P07998 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687292 0.96 TK1 (0.51) TK1RNASE1
Succinic Acid SCHEMBL9386796 0.92 TK1 (0.47) TK1RNASE1
SCHEMBL20636770 0.92 LMNA (0.42) TK1
SCHEMBL5086839 0.87 TK1 (0.46) TK1
SCHEMBL5486401 0.87 LMNA (0.46) TK1
SCHEMBL20840413 0.86 TK1 (0.40) TK1
SCHEMBL2027057 0.86 LMNA (0.49) TK1
SCHEMBL8892071 0.86 TK1 (0.40) TK1
SCHEMBL4626081 0.86 TK1 (0.55) TK1
SCHEMBL2030339 0.85 TK1 (0.38) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0165313-B1 NUCLEIC ACID HYBRIDIZATION ASSAY HRI RESEARCH, INC. (US) 1989-11-15 EP disclosed
US-4599303-A PSORALEN DERIVATIVES HRI ASSOCIATES, INC. (US) 1986-07-08 US disclosed
EP-0165313-A4 NUCLEIC ACID HYBRIDIZATION ASSAY. HRI RES INC (US) 1986-05-16 EP disclosed
EP-0165313-A1 NUCLEIC ACID HYBRIDIZATION ASSAY. HYDROCARBON RESEARCH INC (US) 1985-12-27 EP disclosed
WO-1985002628-A1 NUCLEIC ACID HYBRIDIZATION ASSAY HRI RESEARCH, INC. (US) 1985-06-20 WO disclosed