Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097771 | 0.79 | HDAC3 (0.38) | ALDH1A1IDO1TSHR | |
| SCHEMBL10572441 | 0.73 | ALDH1A1 (0.35) | ALDH1A1IDO1TSHRMAPT | |
| SCHEMBL212550 | 0.72 | ALDH1A1 (0.46) | ALDH1A1IDO1TSHRMAPT | |
| SCHEMBL5433984 | 0.71 | HDAC3 (0.39) | ALDH1A1IDO1TSHRMAPT | |
| SCHEMBL3696389 | 0.71 | HDAC3 (0.39) | ALDH1A1IDO1TSHRMAPT | |
| SCHEMBL8956635 | 0.71 | ALDH1A1 (0.50) | ALDH1A1IDO1TSHR | |
| SCHEMBL2773358 | 0.69 | IDO1 (0.42) | ALDH1A1IDO1TSHRMAPT | |
| SCHEMBL10405414 | 0.69 | CTSK (0.36) | ALDH1A1 | |
| SCHEMBL10463868 | 0.69 | LMNA (0.43) | ALDH1A1IDO1MAPT | |
| SCHEMBL6719581 | 0.68 | IDO1 (0.41) | ALDH1A1IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877795-A | 4H-quinolizin-4-one compounds useful for the treatment of allergic bronchial asthma, allergic rhinitis atropic dermatitis and the like | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0277755-A1 | 4H-quinolizin-4-one compounds exhibiting therapeutic activities | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-08-10 | — | — | EP | disclosed |