Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10574016 | 0.82 | PRKCI (0.47) | PDE4BPDE4DACP1CYP1A2CYP2C19 | |
| SCHEMBL11101954 | 0.79 | KDM4E (0.30) | ALDH1A1 | |
| SCHEMBL11104294 | 0.78 | ALDH1A1 (0.38) | KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL11107790 | 0.77 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL11109506 | 0.76 | HTR1A (0.32) | — | |
| SCHEMBL11103525 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10575968 | 0.72 | PDE4B (0.50) | PDE4BPDE4DMEN1KMT2ATP53 | |
| SCHEMBL11105382 | 0.67 | LMNA (0.45) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27851793 | 0.64 | TNKS2 (0.44) | PDE4BPDE4DMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL9877620 | 0.63 | HTR2C (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871739-A | Substituted 6H-7,8-dihydrothiapyrano(3,2-D)-pyrimidines as hyopglycemic agents | MERCK & CO., INC. (US) | 1989-10-03 | — | — | US | disclosed |