Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.64 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576078 | 0.89 | HDAC6 (0.52) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10573947 | 0.88 | NPC1 (0.58) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10577479 | 0.88 | NPBWR1 (0.67) | NPBWR1DGAT1KCNH2ALDH1A1NPC1 | |
| SCHEMBL10579334 | 0.87 | DGAT1 (0.64) | NPBWR1DGAT1KCNH2ALDH1A1HPGD | |
| SCHEMBL10578018 | 0.86 | DGAT1 (0.62) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10573910 | 0.85 | SLC2A1 (0.62) | NPBWR1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL10256934 | 0.84 | NPBWR1 (0.73) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10580080 | 0.82 | METAP2 (0.75) | KDM4EHPGDNPC1RAB9AMAPT | |
| SCHEMBL4192687 | 0.82 | DGAT1 (0.74) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 | |
| SCHEMBL10578455 | 0.80 | NPBWR1 (0.56) | NPBWR1DGAT1KCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |