Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 14/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578096 | 0.92 | AMY1A (0.37) | SCN10AAMY1APDE5APDE3BPDE3A | |
| SCHEMBL11017158 | 0.84 | PKN1 (0.46) | AMY1AMETAP2 | |
| SCHEMBL10575621 | 0.82 | AMY1A (0.36) | AMY1APDE5APDE3BPDE3A | |
| SCHEMBL10580157 | 0.82 | CDK4 (0.47) | SCN10AAMY1A | |
| SCHEMBL10578739 | 0.80 | AMY1A (0.36) | AMY1APDE5APDE3BPDE3A | |
| SCHEMBL11017149 | 0.78 | MAPK10 (0.41) | AMY1APDE5APDE3BPDE3A | |
| SCHEMBL10765920 | 0.78 | AMY1A (0.39) | AMY1APDE5APDE3BPDE3ADGAT1 | |
| SCHEMBL10742305 | 0.76 | PDE5A (0.47) | AMY1APDE5APDE3BPDE3A | |
| SCHEMBL9703649 | 0.75 | AMY1A (0.43) | AMY1APDE5APDE3BPDE3A | |
| SCHEMBL10852513 | 0.74 | AMY1A (0.40) | AMY1APDE5APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |