Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 7/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580149 | 0.92 | CDK4 (0.41) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL11021898 | 0.84 | ATR (0.53) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10579371 | 0.83 | CDK4 (0.44) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10577395 | 0.82 | CDK4 (0.45) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10578104 | 0.82 | SCN10A (0.41) | SCN10AAMY1A | |
| SCHEMBL11021893 | 0.78 | ATR (0.44) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10760630 | 0.78 | CDK4 (0.43) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL9703335 | 0.76 | CDK4 (0.47) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10677421 | 0.76 | PDE5A (0.50) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10853376 | 0.75 | CDK4 (0.46) | CDK4CCNA2CCND1CDK2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |