Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
| ▸ | CFB | P00751 | 12/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017149 | 0.91 | MAPK10 (0.41) | PKN1PKN2CFBCHEK2AMY1A | |
| SCHEMBL11018557 | 0.89 | PKN1 (0.44) | PKN1PKN2CFBCHEK2METAP2 | |
| SCHEMBL11018070 | 0.89 | METAP2 (0.44) | PKN1PKN2CFBCHEK2METAP2 | |
| SCHEMBL11021164 | 0.87 | PKN1 (0.42) | PKN1PKN2CFBCHEK2METAP2 | |
| SCHEMBL10578104 | 0.84 | SCN10A (0.41) | METAP2AMY1A | |
| SCHEMBL10764183 | 0.83 | MAPK10 (0.41) | PKN1PKN2CFBCHEK2AMY1A | |
| SCHEMBL11021898 | 0.80 | ATR (0.53) | PKN1PKN2CFBCHEK2METAP2 | |
| SCHEMBL11018065 | 0.80 | PDE5A (0.37) | PKN1PKN2CHEK2METAP2METAP1 | |
| SCHEMBL10767330 | 0.80 | MAPK10 (0.39) | PKN1PKN2CFBCHEK2AMY1A | |
| SCHEMBL11019300 | 0.80 | PKN1 (0.48) | PKN1PKN2CFBCHEK2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |