Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 12/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702924 | 0.86 | AMY1A (0.41) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL10852513 | 0.83 | AMY1A (0.40) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL10551908 | 0.83 | AMY1A (0.39) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL9705442 | 0.83 | KDM4E (0.41) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL9704436 | 0.82 | PDE5A (0.43) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL9704539 | 0.82 | AMY1A (0.40) | AMY1APDE5APDE3BPDE3ATP53 | |
| SCHEMBL10373752 | 0.81 | PDE3B (0.48) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL9703335 | 0.81 | CDK4 (0.47) | AMY1APDE5APDE3BPDE3AGRIN2D | |
| SCHEMBL9703428 | 0.80 | PDE3B (0.41) | AMY1APDE5APDE3BPDE3APDE2A | |
| SCHEMBL10742305 | 0.80 | PDE5A (0.47) | AMY1APDE5APDE3BPDE3APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116843-A | Anticoagulants, hypotensive agents and cardiovascular disorder | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-26 | — | — | US | disclosed |