Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 16/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574074 | 0.91 | AMY1A (0.47) | AMY1AADORA2B | |
| SCHEMBL10580044 | 0.85 | AMY1A (0.41) | AMY1ANPBWR1 | |
| SCHEMBL10574102 | 0.84 | AMY1A (0.50) | AMY1AADORA2BNPBWR1HRH4 | |
| SCHEMBL10693991 | 0.79 | AMY1A (0.45) | AMY1ANPBWR1 | |
| SCHEMBL10579204 | 0.79 | ALOX5 (0.62) | AMY1ANPBWR1 | |
| SCHEMBL10576332 | 0.77 | AMY1A (0.38) | AMY1A | |
| SCHEMBL1483091 | 0.76 | AMY1A (0.65) | AMY1A | |
| SCHEMBL10575984 | 0.76 | SCN10A (0.38) | AMY1ANPBWR1 | |
| SCHEMBL10573910 | 0.76 | SLC2A1 (0.62) | NPBWR1 | |
| SCHEMBL10574093 | 0.76 | AMY1A (0.43) | AMY1AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |