Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.48 |
| ▸ | GUSB | P08236 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579198 | 0.91 | ALOX5 (0.53) | ALOX5EPHX2KDM4EALDH1A1HPGD | |
| SCHEMBL10573910 | 0.86 | SLC2A1 (0.62) | KDM4EALDH1A1HPGDCHEK2NPBWR1 | |
| SCHEMBL10576087 | 0.83 | ALOX5 (0.56) | ALOX5EPHX2KDM4EALDH1A1HPGD | |
| SCHEMBL10577479 | 0.82 | NPBWR1 (0.67) | ALDH1A1CHEK2NPBWR1TRPV1 | |
| SCHEMBL10579334 | 0.81 | DGAT1 (0.64) | ALDH1A1HPGDCHEK2NPBWR1TRPV1 | |
| SCHEMBL10576089 | 0.80 | NPBWR1 (0.64) | KDM4EALDH1A1HPGDCHEK2NPBWR1 | |
| SCHEMBL10693991 | 0.79 | AMY1A (0.45) | ALOX5EPHX2AMY1ACHEK2NPBWR1 | |
| SCHEMBL10573947 | 0.79 | NPC1 (0.58) | KDM4EALDH1A1HPGDNPBWR1TRPV1 | |
| SCHEMBL10574081 | 0.79 | AMY1A (0.56) | AMY1ANPBWR1 | |
| SCHEMBL10580044 | 0.77 | AMY1A (0.41) | AMY1ACHEK2NPBWR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |