Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 9/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSH | P09668 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10819021 | 1.00 | CTSB (0.46) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL9716618 | 0.76 | CPB2 (0.55) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL7890166 | 0.76 | CPB2 (0.55) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL28335157 | 0.75 | GSR (0.44) | — | |
| SCHEMBL7751944 | 0.74 | DPP7 (0.50) | — | |
| SCHEMBL7751947 | 0.74 | DPP7 (0.50) | — | |
| SCHEMBL10580958 | 0.74 | HDAC3 (0.40) | — | |
| SCHEMBL1328597 | 0.74 | SIRT6 (0.44) | — | |
| SCHEMBL5155641 | 0.74 | GSR (0.38) | — | |
| SCHEMBL1661759 | 0.74 | SIRT6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833152-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1989-05-23 | — | — | US | claimed |
| US-4734420-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | UNIVERSITY OF MIAMI (US) | 1988-03-29 | — | — | US | claimed |
| US-4692459-A | SULFUR CONTAINING AMINO ACID DERIVATIVES, ANGIOTENSIN INHIBITOR | UNIVERSITY OF MIAMI (US) | 1987-09-15 | — | — | US | claimed |
| US-4692437-A | SALTS OF THIOPROLINE COMPOUNDS | UNIVERSITY OF MIAMI (US) | 1987-09-08 | — | — | US | claimed |
| US-4692458-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1987-09-08 | — | — | US | claimed |
| US-4690936-A | AMINO ACIDS, THIOESTER LINKAGE; ANGIOTENSIN INHIBITORS | UNIVERSITY OF MIAMI (US) | 1987-09-01 | — | — | US | claimed |
| US-4690940-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1987-09-01 | — | — | US | claimed |
| EP-0035383-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-05-30 | — | — | EP | claimed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0009898-B1 | NOVEL ANTI-HYPERTENSIVE MERCAPTOACYLAMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | UNIVERSITY OF MIAMI (US) | 1983-05-18 | — | — | EP | claimed |
| EP-0038117-A1 | Methods for preparing anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1981-10-21 | — | — | EP | claimed |
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | claimed |
| EP-0035383-A1 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-09 | — | — | EP | claimed |
| EP-0009898-A1 | Novel anti-hypertensive mercaptoacylamino acid derivatives, their preparation and use | UNIVERSITY OF MIAMI (US) | 1980-04-16 | — | — | EP | claimed |
| JP-1246257-A | — | — | None | — | — | JP | disclosed |
| JP-H01246257-A | PRODUCTION OF 3-THIOPROPIONIC ACID DERIVATIVE | UNIV MIAMI | 1989-10-02 | — | — | JP | disclosed |
| US-4833152-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0035383-A1 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-09 | — | — | EP | disclosed |
| EP-0009898-A1 | Novel anti-hypertensive mercaptoacylamino acid derivatives, their preparation and use | UNIVERSITY OF MIAMI (US) | 1980-04-16 | — | — | EP | disclosed |
| EP-0009898-A1 | Novel anti-hypertensive mercaptoacylamino acid derivatives, their preparation and use | UNIVERSITY OF MIAMI (US) | 1980-04-16 | — | — | EP | disclosed |