Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | ARAF | P10398 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554060 | 0.91 | KMT2A (0.59) | BRAFHDAC1RAF1ARAFKDM4E | |
| SCHEMBL29380973 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPOLBKMT2AGFER | |
| SCHEMBL221141 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPOLBKMT2AGFER | |
| SCHEMBL27720018 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPOLBKMT2AGFER | |
| SCHEMBL712251 | 0.89 | KDM4E (0.61) | BRAFHDAC1RAF1ARAFKDM4E | |
| SCHEMBL710634 | 0.86 | KMT2A (0.63) | BRAFHDAC1RAF1ARAFSMN1; SMN2 | |
| SCHEMBL5078313 | 0.86 | POLB (0.57) | BRAFHDAC1KDM4EPOLBKMT2A | |
| SCHEMBL1027446 | 0.86 | KMT2A (0.61) | BRAFHDAC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL523820 | 0.84 | POLB (0.63) | SMN1; SMN2KDM4EPOLBRXFP1PARP10 | |
| SCHEMBL2426327 | 0.83 | KEAP1 (0.66) | BRAFHDAC1RAF1ARAFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847365-A | POLYAMIDES, POLYESTERS, OLEFIN POLYMERS | CIBA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |