Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554060 | 0.94 | KMT2A (0.59) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL1553285 | 0.93 | KDM4E (0.55) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL712251 | 0.93 | KDM4E (0.61) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL28250577 | 0.91 | HDAC3 (0.55) | POLBHDAC3BRAFHDAC4HDAC1 | |
| SCHEMBL710634 | 0.89 | KMT2A (0.63) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL1027446 | 0.89 | KMT2A (0.61) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL28315270 | 0.88 | PYGL (0.59) | POLBIDO1HDAC3BRAFHDAC4 | |
| SCHEMBL2661681 | 0.88 | PARP10 (0.58) | POLBHDAC3BRAFHDAC4HDAC1 | |
| SCHEMBL10583194 | 0.86 | BRAF (0.56) | POLBHDAC3BRAFHDAC4HDAC1 | |
| SCHEMBL2426327 | 0.86 | KEAP1 (0.66) | POLBIDO1HDAC3BRAFHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101681099-B | Positive photosensitive resin composition and polyhydroxyamide resin | NISSAN CHEMICAL IND LTD | 2013-02-20 | — | — | CN | disclosed |
| CN-101445487-A | Preparation method of 3H-quinazoline-4-ketones compounds | UNIV SHANGHAI (CN) | 2009-06-03 | — | — | CN | disclosed |
| US-7429677-B2 | Small molecule entry inhibitors | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-09-30 | — | — | US | disclosed |
| EP-1940805-A1 | BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2008-07-09 | — | — | EP | disclosed |
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
| WO-2007022638-A1 | BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007022638-A1 | BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-03-01 | — | — | WO | disclosed |
| US-20040048188-A1 | Positive photosensitive polyimide resin composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-0183651-B1 | METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | disclosed |
| US-4847365-A | POLYAMIDES, POLYESTERS, OLEFIN POLYMERS | CIBA-GEIGY CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0183651-A2 | Metal complexes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | HDAC5, HDAC4, HDAC3 | POLB 1435/4885IDO1 1753/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.