SCHEMBL1058675

SCHEMBL1058675

CCC(c1ccccc1)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
KCNN4 O15554 1/20 0.39
GRIN1 Q05586 4/20 0.39
GRIN2A Q12879 4/20 0.39
GRIN2D O15399 3/20 0.39
GRIN2C Q14957 3/20 0.39
GRIN2B Q13224 2/20 0.39
TAAR1 Q96RJ0 4/20 0.35
HTR2A P28223 2/20 0.35
HRH1 P35367 1/20 0.35
RIPK1 Q13546 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
KIF11 P52732 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1058678 1.00 LMNA (0.40) LMNAKCNN4GRIN1GRIN2AGRIN2D
SCHEMBL6284917 0.77 GRIN1 (0.44) KCNN4GRIN1GRIN2AGRIN2DGRIN2C
Water SCHEMBL28973054 0.77 TAAR1 (0.48) KCNN4TAAR1HTR2AHRH1KIF11
SCHEMBL4454908 0.76 GRIN1 (0.43) LMNAKCNN4GRIN1GRIN2AGRIN2D
SCHEMBL416118 0.76 GRIN1 (0.47) LMNAKCNN4GRIN1GRIN2AGRIN2D
SCHEMBL9817040 0.75 LMNA (0.44) LMNATAAR1HTR2AHRH1RIPK1
SCHEMBL12809670 0.74 GRIN1 (0.42) KCNN4GRIN1GRIN2AGRIN2DGRIN2C
SCHEMBL9493203 0.73 LMNA (0.43) LMNATAAR1HTR2AHRH1RIPK1
SCHEMBL28072057 0.71 LMNA (0.38) LMNAKCNN4GRIN1GRIN2AGRIN2D
SCHEMBL1059025 0.70 MAPK1 (0.42) KCNN4TAAR1HRH1RIPK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2500088-A2 Molecular recognition material and production method thereof Shiseido Co., Ltd. (JP) 2012-09-19 EP disclosed
US-20110021347-A1 Molecule Recognizing Material And Process For Producing The Molecule Recognizing Material KEIO UNIVERSITY (JP) 2011-01-27 US disclosed
EP-2198952-A1 MOLECULE RECOGNIZING MATERIAL AND PROCESS FOR PRODUCING THE MOLECULE RECOGNIZING MATERIAL Keio University (JP) 2010-06-23 EP disclosed