SCHEMBL5079313

SCHEMBL5079313

CC(c1ccccc1)(c1ccccc1)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
MAPK1 P28482 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
PTPN1 P18031 1/20 0.41
CYP3A4 P08684 1/20 0.41
KCNN4 O15554 3/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
KIF11 P52732 1/20 0.39
HSD11B1 P28845 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20762299 0.87 ESR1 (0.63) ALDH1A1TSHRESR1ESR2CYP3A4
SCHEMBL25981607 0.87 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL10705111 0.83 CA4 (0.48) ALDH1A1CA1CA2CA9MAPT
SCHEMBL8571104 0.82 MAPK1 (0.50) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL1058732 0.82 MAPK1 (0.55) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL13518151 0.79 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL4600929 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL12339111 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL20002043 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL13554 0.77 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1TAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820893-B2 Polymer film and preparation method thereof SK MICROWORKS CO., LTD. (KR) 2023-11-21 US disclosed
US-20230234933-A1 EPOXY COMPOUND, COMPOSITION AND CURED PRODUCT THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-07-27 US disclosed
US-10026983-B2 Polymer electrolyte material, polymer electrolyte molded product using the polymer electrolyte material and method for manufacturing the polymer electrolyte molded product, membrane electrode composite, and solid polymer fuel cell TORAY INDUSTRIES, INC. (JP) 2018-07-17 US disclosed
US-9897915-B2 Photosensitive resin composition, method for producing heat-resistant resin film and display device TORAY INDUSTRIES, INC. (JP) 2018-02-20 US disclosed
US-9850346-B2 Transparent polyimide and precursor thereof MITSUI CHEMICALS, INC. (JP) 2017-12-26 US disclosed
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME TORAY INDUSTRIES, INC. (JP) 2017-11-23 US disclosed
US-20170320021-A1 POLYMER-ION-PERMEABLE MEMBRANE, COMPOSITE-ION-PERMEABLE MEMBRANE, BATTERY ELECTROLYTE MEMBRANE, AND ELECTRODE COMPOSITE TORAY INDUSTRIES, INC. (JP) 2017-11-09 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-20170246773-A1 OPTICAL FILM AND METHOD OF PREPARING OPTICAL FILM SAMSUNG ELECTRONICS CO LTD (KR) 2017-08-31 US disclosed
US-20170222243-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT USING THE POLYMER ELECTROLYTE MATERIAL AND METHOD FOR MANUFACTURING THE POLYMER ELECTROLYTE MOLDED PRODUCT, MEMBRANE ELECTRODE COMPOSITE, AND SOLID POLYMER FUEL CELL TORAY INDUSTRIES, INC. 2017-08-03 US disclosed
US-8373287-B2 2013-02-12 US disclosed
EP-1798795-B1 POLYELECTROLYTE MATERIAL, POLYELECTROLYTE COMPONENT, MEMBRANE ELECTRODE COMPOSITE BODY, AND POLYELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES (JP) 2012-08-22 EP disclosed
US-20120129076-A1 Novel Sulfonic Acid Group-Containing Segmented Block Copolymer and Use Thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-05-24 US disclosed
US-20110260343-A1 POLYMERIC COMPOSITIONS COMPRISING PER(PHENYLETHYNYL) ARENE DERIVATIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-10-27 US disclosed
US-20110229828-A1 AROMATIC RING CONTAINING POLYMER, UNDERLAYER COMPOSITION INCLUDING THE SAME, AND ASSOCIATED METHODS CHEIL INDUSTRIES, INC. (KR) 2011-09-22 US disclosed
US-20110065021-A1 Novel Sulfonic-Acid-Group-Containing Segmented Block Copolymer, Application Thereof, and Method of Manufacturing Novel Block Copolymer TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-03-17 US disclosed
WO-2010019488-A1 POLYMERIC COMPOSITIONS COMPRISING PER(PHENYLETHYNYL) ARENE DERIVATIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 2010-02-18 WO disclosed
US-20090124759-A1 CROSSLINKABLE COMPOSITION AND MOLDED ARTICLE MADE OF SAME DAIKIN INDUSTRIES, LTD. (JP) 2009-05-14 US disclosed
WO-2008133884-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS COMBINATORX, INCORPORATED (US) 2008-11-06 WO disclosed
WO-1996014283-A1 PROCESS AND INTERMEDIATES FOR PREPARING TRIPHENYLTRIFLUOROPROPANES AND -PROPENES EGIS Gyógyszergyár Rt. (HU) 1996-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same INO80C, INCENP, PUF60 ALDH1A1 3767/4885TSHR 4239/4885MAPK1 3143/4885
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME HEATR1, HSF1, RER1 ALDH1A1 228/4885TSHR 4182/4885MAPK1 728/4885
US-20230234933-A1 EPOXY COMPOUND, COMPOSITION AND CURED PRODUCT THEREOF FTO, ALKBH3, EGLN1 ALDH1A1 507/4885TSHR 3832/4885MAPK1 4025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.