Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589349 | 0.84 | PPARG (0.47) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL8330503 | 0.74 | ACHE (0.38) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL8900515 | 0.69 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL2692039 | 0.68 | PPARG (0.53) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL11093755 | 0.67 | KDM4E (0.34) | — | |
| SCHEMBL4253889 | 0.67 | HSD17B10 (0.58) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL10718048 | 0.66 | HSD17B10 (0.60) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL6954649 | 0.66 | HSD17B10 (0.60) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL6954317 | 0.66 | HSD17B10 (0.60) | ACHEPPARGESR2AGTR1AGTR2 | |
| SCHEMBL4256521 | 0.66 | HSD17B10 (0.60) | ACHEPPARGESR2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |