Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589349 | 0.79 | PPARG (0.47) | ACHEESR2PPARGGRIA2GRIA4 | |
| SCHEMBL10587607 | 0.74 | ACHE (0.42) | ACHEESR2PPARGGRIA2GRIA4 | |
| SCHEMBL8305889 | 0.69 | ACHE (0.37) | ACHEESR2PPARGGRIA2GRIA4 | |
| SCHEMBL986459 | 0.66 | AGTR1 (0.49) | PPARGAGTR1AGTR2APLNR | |
| Decane SCHEMBL9620442 | 0.65 | ESR2 (0.53) | ACHEESR2PPARGGRIA2GRIA4 | |
| Octane SCHEMBL9620215 | 0.65 | ESR2 (0.53) | ACHEESR2PPARGGRIA2GRIA4 | |
| SCHEMBL2692039 | 0.64 | PPARG (0.53) | ACHEESR2PPARGGRIA2GRIA4 | |
| SCHEMBL11093755 | 0.64 | KDM4E (0.34) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL4253889 | 0.63 | HSD17B10 (0.58) | ACHEESR2PPARGAGTR1AGTR2 | |
| SCHEMBL6959613 | 0.63 | ESR2 (0.51) | ESR2PPARGKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655220-B2 | Process for the preparation of angiotensin II receptor blockers | HETERO LABS LIMITED (IN) | 2023-05-23 | — | — | US | disclosed |
| US-20220127238-A1 | PROCESS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR BLOCKERS | HETERO LABS LIMITED (IN) | 2022-04-28 | — | — | US | disclosed |
| US-5962500-A | HYPOSENSITVE AGENT | MERCK SHARP & DOHME CORP. | 1999-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127238-A1 | PROCESS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR BLOCKERS | AGTR2, AGTR1, ADRB1 | ACHE 2278/4885ESR2 719/4885PPARG 1589/4885 |
| US-11655220-B2 | Process for the preparation of angiotensin II receptor blockers | AGTR2, AGTR1, ADRB1 | ACHE 2278/4885ESR2 719/4885PPARG 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.