Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719544 | 0.87 | MAPT (0.75) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL12575384 | 0.84 | MAPT (0.75) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL12781849 | 0.83 | LMNA (0.68) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9493281 | 0.82 | LMNA (0.67) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL7291269 | 0.82 | LMNA (0.67) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL30874651 | 0.82 | IGF1R (0.64) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL14355266 | 0.82 | MEN1 (0.50) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL9015935 | 0.79 | ALDH1A1 (0.74) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL10587768 | 0.79 | IGF1R (0.64) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL10147158 | 0.79 | IGF1R (0.59) | MEN1KMT2APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291624-B2 | CDK-inhibitory pyrimidines, their production and use as pharmaceutical agents | BAYER SCHERING PHARMA AG (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7235561-B2 | Compound and a composition including such a compound | SCHERING AG (DE) | 2007-06-26 | — | — | US | disclosed |