Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076986 | 0.87 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9079344 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL30945216 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL28203039 | 0.81 | KCNK3 (0.51) | HSD11B1HTR2AHTR2CKCNH2LMNA | |
| SCHEMBL8669709 | 0.80 | DRD2 (0.56) | MEN1KMT2AHTR2AHTR2CKCNH2 | |
| SCHEMBL6349754 | 0.76 | LMNA (0.57) | MEN1KMT2AHSD11B1KDM4ELMNA | |
| SCHEMBL20248643 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACTSKKDM4E | |
| SCHEMBL8544632 | 0.75 | CTSK (0.48) | ALDH1A1HTR2AHTR2CKCNH2SIGMAR1 | |
| SCHEMBL8544630 | 0.75 | CTSK (0.48) | ALDH1A1HTR2AHTR2CKCNH2SIGMAR1 | |
| SCHEMBL5172227 | 0.75 | KDM4E (0.64) | HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325268-A1 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-07-26 | — | — | EP | claimed |