SCHEMBL6349754

SCHEMBL6349754

O=C(c1ccc(F)cc1)C1CCCCN1CC(O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
SCD O00767 1/20 0.44
KDM4E B2RXH2 2/20 0.43
HSD11B1 P28845 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PTGER4 P35408 2/20 0.42
CCR5 P51681 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706569 0.83 HSD11B1 (0.41) LMNAHSD11B1MEN1KMT2APTGER4
SCHEMBL5759297 0.81 CCR5 (0.44) KDM4EHSD11B1PTGER4CCR5
SCHEMBL10726480 0.77 HTR2A (0.59) LMNASCDKDM4EHSD11B1
SCHEMBL10722254 0.77 HTR2A (0.59) LMNASCDKDM4EHSD11B1
SCHEMBL10722200 0.77 HTR2A (0.59) LMNASCDKDM4EHSD11B1
SCHEMBL10587794 0.76 ALDH1A1 (0.46) LMNAKDM4EHSD11B1MEN1KMT2A
SCHEMBL8669709 0.76 DRD2 (0.56) KDM4EMEN1KMT2A
SCHEMBL5172227 0.76 KDM4E (0.64) KDM4E
SCHEMBL7410657 0.75 PTGER4 (0.54) KDM4EPTGER4
Hydrochloric Acid SCHEMBL28203039 0.74 KCNK3 (0.51) LMNAHSD11B1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050080268-A1 Process of preparing O-carbamoyl compounds in the presence of active amine group SK CORPORATION (KR) 2005-04-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080268-A1 Process of preparing O-carbamoyl compounds in the presence of active amine group CBR3, ARG1, ODC1 LMNA 3459/4885SCD 1328/4885KDM4E 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.