Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906683 | 0.94 | CA2 (0.50) | CA2CA12CA9TP53MAPT | |
| SCHEMBL5518610 | 0.89 | PTGS2 (0.50) | CA2CA12CA9PTGS2LMNA | |
| SCHEMBL5518603 | 0.89 | CA2 (0.67) | CA2CA12CA9LMNAMMP1 | |
| SCHEMBL2006278 | 0.89 | PTGS2 (0.50) | CA2CA12CA9PTGS2LMNA | |
| SCHEMBL5527319 | 0.89 | CA2 (0.67) | CA2CA12CA9LMNAMMP1 | |
| SCHEMBL5527318 | 0.89 | PTGS2 (0.50) | CA2CA12CA9PTGS2LMNA | |
| SCHEMBL9356008 | 0.89 | CA2 (0.67) | CA2CA12CA9LMNAMMP1 | |
| SCHEMBL14432683 | 0.83 | PTGS2 (0.48) | CA2CA12CA9PTGS2MMP1 | |
| SCHEMBL30072318 | 0.82 | HSD11B1 (0.55) | CA2LMNAPKMMMP1MMP2 | |
| SCHEMBL4328574 | 0.82 | HSD11B1 (0.55) | CA2LMNAPKMMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322151-A2 | Aromatic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-06-28 | — | — | EP | disclosed |