SCHEMBL2006278

SCHEMBL2006278

O=S(=O)(c1ccc(F)cc1)c1ccc(-c2ccc(S(=O)(=O)c3ccc(F)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.50
PTGS1 P23219 5/20 0.50
MMP1 P03956 2/20 0.50
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
MMP13 P45452 2/20 0.50
HSD11B1 P28845 1/20 0.50
MMP3 P08254 1/20 0.50
MMP12 P39900 1/20 0.50
MMP14 P50281 1/20 0.50
CA2 P00918 2/20 0.48
CA1 P00915 1/20 0.48
MMP8 P22894 1/20 0.48
HTR2C P28335 2/20 0.47
HTR2A P28223 2/20 0.47
KCNH2 Q12809 2/20 0.47
HTR2B P41595 1/20 0.47
CYP3A4 P08684 2/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518610 1.00 PTGS2 (0.50) PTGS2PTGS1MMP1MMP2MMP9
SCHEMBL5527318 1.00 PTGS2 (0.50) PTGS2PTGS1MMP1MMP2MMP9
SCHEMBL14432683 0.93 PTGS2 (0.48) PTGS2PTGS1MMP1MMP2MMP9
SCHEMBL2121770 0.92 HSD11B1 (0.55) MMP1MMP2MMP9MMP13HSD11B1
SCHEMBL4328574 0.92 HSD11B1 (0.55) MMP1MMP2MMP9MMP13HSD11B1
SCHEMBL79787 0.92 HSD11B1 (0.55) MMP1MMP2MMP9MMP13HSD11B1
SCHEMBL30072318 0.92 HSD11B1 (0.55) MMP1MMP2MMP9MMP13HSD11B1
SCHEMBL7929318 0.91 MMP1 (0.57) PTGS2PTGS1MMP1MMP2MMP9
SCHEMBL7938152 0.91 HTR6 (0.61) PTGS2PTGS1MMP1MMP2MMP9
SCHEMBL11589056 0.89 ALDH1A1 (0.67) PTGS2CYP3A4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN claimed
CN-114539108-A Synthesis method of 4, 4' -bis (4-fluorophenylsulfonyl) biphenyl 营口兴福化工有限公司 2022-05-27 CN claimed
US-7834134-B2 Polyarylethers, blends and methods for making GENERAL ELECTRIC COMPANY (US) 2010-11-16 US claimed
US-20100041838-A1 POLYARYLETHERS, BLENDS AND METHODS FOR MAKING BL TECHNOLOGIES, INC. 2010-02-18 US claimed
US-20100041837-A1 POLYARYLETHERS, BLENDS AND METHODS FOR MAKING GENERAL ELECTRIC COMPANY 2010-02-18 US claimed
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN disclosed
EP-4306602-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-01-17 EP disclosed
US-20230399528-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2023-12-14 US disclosed
CN-116997620-A Powder primer composition 大金工业株式会社 2023-11-03 CN disclosed
US-20220340755-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES CYTIVA SWEDEN AB (SE) 2022-10-27 US disclosed
US-11407897-B2 Zwitterion-functionalized multicomponent copolymers and associated polymer blends and membranes CYTIVA SWEDEN AB (SE) 2022-08-09 US disclosed
CN-114539108-A Synthesis method of 4, 4' -bis (4-fluorophenylsulfonyl) biphenyl 营口兴福化工有限公司 2022-05-27 CN disclosed
US-4877682-A OUTSIDE SHEETS HAVE HIGHER STIFFNESS AMOCO CORPORATION (US) 1989-10-31 US disclosed
EP-0263854-A4 LAMINATES CONTAINING COEXTRUDED SCRAP. AMOCO CORP (US) 1988-11-02 EP disclosed
US-4772653-A Stain resistant cookware from blends comprising an interpolymer of an unsaturated dicarboxylic acid compound AMOCO CORPORATION (US) 1988-09-20 US disclosed
EP-0263854-A1 LAMINATES CONTAINING COEXTRUDED SCRAP AMOCO CORPORATION (US) 1988-04-20 EP disclosed
WO-1987005853-A1 LAMINATES CONTAINING COEXTRUDED SCRAP AMOCO CORPORATION (US) 1987-10-08 WO disclosed
EP-0216513-A2 Treatment of drilled copper-clad thermoplastic laminates AMOCO CORPORATION (US) 1987-04-01 EP disclosed
US-4625000-A SULFONATED WITH SILYL HALOSULFONATE THEN CLEAVAGE OF SILYL GROUP UNION CARBIDE CORPORATION (US) 1986-11-25 US disclosed
US-4169178-A A BISPHENOL OR -DIPHENYL ETHER, SULFIDE, SULFONE, OR KETONE AND A DIHALOBENZENOID COMPOUND AND/OR AN O- OR P-SULFONE- OR KETO-ACTIVATED HALOPHENOL WITH AN ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-09-25 US disclosed