SCHEMBL4328574

SCHEMBL4328574

O=S(=O)(c1ccc(F)cc1)c1ccc(S(=O)(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.55
MMP2 P08253 2/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
MMP1 P03956 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
CYP3A4 P08684 2/20 0.52
HTR6 P50406 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
GAA P10253 1/20 0.52
HTR2A P28223 4/20 0.52
KCNH2 Q12809 4/20 0.52
HTR2C P28335 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30072318 1.00 HSD11B1 (0.55) HSD11B1MMP2CA1CA2MMP1
SCHEMBL79787 1.00 HSD11B1 (0.55) HSD11B1MMP2CA1CA2MMP1
SCHEMBL2121770 1.00 HSD11B1 (0.55) HSD11B1MMP2CA1CA2MMP1
SCHEMBL5527318 0.92 PTGS2 (0.50) HSD11B1MMP2CA1CA2MMP1
SCHEMBL5518610 0.92 PTGS2 (0.50) HSD11B1MMP2CA1CA2MMP1
SCHEMBL2006278 0.92 PTGS2 (0.50) HSD11B1MMP2CA1CA2MMP1
SCHEMBL778229 0.89 HTR6 (0.70) HSD11B1MMP2CA1CA2MMP1
SCHEMBL11980110 0.89 HTR6 (0.70) HSD11B1MMP2CA1CA2MMP1
SCHEMBL7937274 0.89 HTR6 (0.70) HSD11B1MMP2CA1CA2MMP1
SCHEMBL719303 0.87 GAA (0.55) HSD11B1MMP2CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN claimed
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN disclosed
EP-4306602-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-01-17 EP disclosed
US-20230399528-A1 POWDERY PRIMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2023-12-14 US disclosed
CN-116997620-A Powder primer composition 大金工业株式会社 2023-11-03 CN disclosed
WO-2022191049-A1 POWDERY PRIMER COMPOSITION ダイキン工業株式会社 2022-09-15 WO disclosed
CN-114437358-A Polymer resin with polyethylene glycol side chain, preparation method thereof and power storage electrode 吉林大学 2022-05-06 CN disclosed
US-20090156720-A1 Polyethersulfone-Based Resin Composition and Molded Article Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-18 US disclosed
WO-2008005647-A2 SULFONATED POLYARYLETHERKETONE-BLOCK-POLYETHERSULFONE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-01-10 WO disclosed
US-20080004443-A1 Sulfonated polyaryletherketone-block-polyethersulfone copolymers GENERAL ELECTRIC COMPANY 2008-01-03 US disclosed
US-5194561-A PROCESS FOR THE PREPARATION OF AN AROMATIC POLYETHER IN THE PRESENCE OF FINELY DIVIDED CONDENSATION AUXILIARIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
US-5081214-A Mixture of Sodium Carbonate and Sodium Bicarbonate HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed
US-5047496-A N-alkylated acid amide solvents; etherification BAYER AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0412498-A2 Process for preparation of an aromatic polyether HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-13 EP disclosed
EP-0412499-A2 Process for the preparation of an aromatic polyether in the presence of finely dispersed condensation agents HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-13 EP disclosed
EP-0404724-A2 Polyarylenethers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-27 EP disclosed
EP-0347669-A2 Method for producing aromatic polyether sulfones BAYER AG (DE) 1989-12-27 EP disclosed
US-4636557-A Process for the preparation of aromatic polyethers with mixture of carbonate catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1987-01-13 US disclosed
EP-0143407-B1 PROCESS FOR PREPARING AROMATIC POLYETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-12 EP disclosed
EP-0143407-A2 Process for preparing aromatic polyethers HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004443-A1 Sulfonated polyaryletherketone-block-polyethersulfone copolymers ABCB7, AKR1B10, RER1 HSD11B1 199/4885MMP2 4645/4885CA1 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.