Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768781 | 0.83 | OPRM1 (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL28414033 | 0.80 | HCAR3 (0.37) | HCAR3HCAR2MEN1CYP1A2POLB | |
| SCHEMBL7145685 | 0.77 | TDP1 (0.41) | MEN1TSHRKMT2ATDP1GRIN1 | |
| SCHEMBL8971038 | 0.70 | CYP3A4 (0.33) | CYP3A4MAPK1 | |
| SCHEMBL28193546 | 0.69 | CHRNB2 (0.36) | MEN1CYP1A2KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL28585875 | 0.68 | HCAR3 (0.43) | HCAR3HCAR2MEN1CYP1A2POLB | |
| SCHEMBL9692301 | 0.67 | HTT (0.45) | HCAR3HCAR2MEN1POLBTSHR | |
| SCHEMBL14967939 | 0.66 | TSHR (0.48) | HCAR3HCAR2MEN1CYP1A2TSHR | |
| SCHEMBL14967432 | 0.65 | ELANE (0.38) | HCAR3HCAR2POLBTSHRTDP1 | |
| SCHEMBL27171590 | 0.64 | KDM1A (0.37) | HCAR3HCAR2MEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324569-A2 | Process for preparing functionalized polymeric compositions | ROHM AND HAAS COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |