SCHEMBL28414033

SCHEMBL28414033

CCC1(c2ccccc2)OC1CO

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
PTGS2 P35354 1/20 0.34
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
APEX1 P27695 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902463 0.82 MMP2 (0.43)
SCHEMBL10588286 0.80 HCAR3 (0.33) HCAR3HCAR2CYP3A4MAPK1MEN1
SCHEMBL28117405 0.76 CYP3A4 (0.38) HCAR3HCAR2CYP3A4MAPK1PTGS2
SCHEMBL4082290 0.73 CYP3A4 (0.40) HCAR3HCAR2CYP3A4MAPK1PTGS2
SCHEMBL12319751 0.73 CYP3A4 (0.40) HCAR3HCAR2CYP3A4MAPK1PTGS2
SCHEMBL13343386 0.73 CYP3A4 (0.40) HCAR3HCAR2CYP3A4MAPK1PTGS2
SCHEMBL28585875 0.73 HCAR3 (0.43) HCAR3HCAR2MEN1CYP1A2POLB
SCHEMBL13258813 0.72 PTGS2 (0.38) CYP3A4MAPK1PTGS2HSP90AA1MAPT
SCHEMBL3720343 0.72 PTGS2 (0.38) CYP3A4MAPK1PTGS2HSP90AA1MAPT
SCHEMBL28218097 0.72 THRB (0.40) HCAR3HCAR2CYP3A4MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661498-B Isomeric mixtures of musk compounds having an unsaturated macrocyclic ring 西姆莱斯有限公司 2021-11-23 CN disclosed
CN-106535866-B E isomer-enriched mixtures of musk compounds having an unsaturated macrocyclic ring 西姆莱斯有限公司 2020-05-15 CN disclosed