Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765002 | 0.80 | GPR3 (0.46) | NOTUMS100A4ACHETTRCES1 | |
| SCHEMBL5835789 | 0.75 | NOTUM (0.64) | NOTUMCES1ALDH1A1KDM4EMAPT | |
| SCHEMBL221250 | 0.75 | NOTUM (0.64) | NOTUMCES1ALDH1A1KDM4EMAPT | |
| SCHEMBL22292629 | 0.73 | NOTUM (0.53) | NOTUMKMT2AMEN1HTR2CHTR2A | |
| SCHEMBL14305775 | 0.71 | ALDH1A1 (0.39) | NOTUMS100A4CES1KMT2AMEN1 | |
| SCHEMBL5397337 | 0.71 | LMNA (0.51) | NOTUMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6649103 | 0.69 | BCHE (0.43) | NOTUMALDH1A1LMNA | |
| SCHEMBL30346306 | 0.69 | BCHE (0.43) | NOTUMALDH1A1LMNA | |
| SCHEMBL29866320 | 0.68 | NOTUM (0.42) | NOTUMS100A4TTRCES1TSHR | |
| SCHEMBL8229278 | 0.67 | KCNN4 (0.55) | KMT2AHTR2CHTR2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | disclosed |