Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566816 | 0.78 | MAPT (0.43) | MEN1KMT2ACDK5CDK5R1CYP3A4 | |
| SCHEMBL8562265 | 0.77 | MAPT (0.48) | KMT2AMAPTMGMTMAPK1ALDH1A1 | |
| SCHEMBL8599452 | 0.74 | MAPT (0.43) | MEN1KMT2AATMGSK3AGSK3B | |
| SCHEMBL8567950 | 0.74 | CYP3A4 (0.47) | MEN1KMT2ACYP3A4MAPTMGMT | |
| SCHEMBL8596689 | 0.72 | TLR8 (0.61) | ATMTLR7MAPTALDH1A1 | |
| SCHEMBL8564398 | 0.72 | POLB (0.43) | MEN1KMT2ATLR7MAPTMGMT | |
| SCHEMBL27842115 | 0.72 | TLR8 (0.45) | MEN1KMT2ACDK5CDK5R1MAPT | |
| SCHEMBL3953291 | 0.72 | KDM4E (0.52) | MEN1KMT2ACYP3A4MAPTMGMT | |
| Ammonia Solution, Strong SCHEMBL5858299 | 0.71 | MEN1 (0.38) | MEN1KMT2AATMGSK3AGSK3B | |
| SCHEMBL8567514 | 0.70 | S100A4 (0.54) | MEN1KMT2ACDK5CDK5R1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| EP-0145340-A2 | 1H-Imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1985-06-19 | — | — | EP | disclosed |