Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778090 | 0.86 | HSD17B10 (0.56) | KMT2AALDH1A1HPGDMEN1NPSR1 | |
| SCHEMBL10594053 | 0.81 | CASP3 (0.43) | RPS6KA2KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL10593868 | 0.76 | CA12 (0.44) | KMT2AALDH1A1HPGDMEN1MAPT | |
| SCHEMBL9777952 | 0.76 | HSD17B10 (0.53) | KMT2AALDH1A1HPGDNPSR1TP53 | |
| SCHEMBL9778019 | 0.75 | ALDH1A1 (0.46) | KMT2AALDH1A1HPGDMEN1MAPT | |
| SCHEMBL9778058 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNA | |
| SCHEMBL13416394 | 0.71 | KMT2A (0.51) | RPS6KA2KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL18651719 | 0.70 | KMT2A (0.48) | RPS6KA2KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL11862277 | 0.70 | KDM4E (0.74) | RPS6KA2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL14960666 | 0.70 | KMT2A (0.50) | RPS6KA2KMT2AALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |