Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778058 | 0.84 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10593868 | 0.82 | CA12 (0.44) | CASP3MMP2MMP9KMT2AMEN1 | |
| SCHEMBL10591053 | 0.81 | RPS6KA2 (0.54) | CASP3KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL9778019 | 0.81 | ALDH1A1 (0.46) | CASP3KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL17260672 | 0.75 | CASP3 (0.59) | CASP3ALDH1A1CA1CA2CA9 | |
| SCHEMBL9778090 | 0.73 | HSD17B10 (0.56) | KMT2AMEN1MAPK1ALDH1A1TDP1 | |
| SCHEMBL28131612 | 0.72 | SIGMAR1 (0.48) | — | |
| SCHEMBL13416394 | 0.71 | KMT2A (0.51) | CASP3KMT2AMAPK1ALDH1A1RPS6KA2 | |
| SCHEMBL18651719 | 0.70 | KMT2A (0.48) | CASP3DRD3KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14960666 | 0.70 | KMT2A (0.50) | CASP3KMT2AMAPK1ALDH1A1RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |