Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777952 | 0.91 | HSD17B10 (0.53) | HSD17B10POLBAPEX1TDP1PTPN1 | |
| SCHEMBL9777995 | 0.86 | HSD17B10 (0.55) | HSD17B10POLBAPEX1TDP1PTPN1 | |
| SCHEMBL10591053 | 0.86 | RPS6KA2 (0.54) | TDP1ALDH1A1HPGDKMT2ANPSR1 | |
| SCHEMBL11379270 | 0.77 | POLB (0.63) | HSD17B10POLBAPEX1TDP1PTPN1 | |
| SCHEMBL9778019 | 0.75 | ALDH1A1 (0.46) | POLBALDH1A1HPGDKMT2AGAA | |
| SCHEMBL10593868 | 0.74 | CA12 (0.44) | ALDH1A1HPGDKMT2AGAAMAPT | |
| SCHEMBL9778058 | 0.74 | ALDH1A1 (0.43) | PTPN1ALDH1A1MAPT | |
| SCHEMBL10594053 | 0.73 | CASP3 (0.43) | TDP1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL12742268 | 0.73 | GAA (0.57) | HSD17B10POLBTDP1PTPN1ALDH1A1 | |
| SCHEMBL13140924 | 0.72 | MAPT (0.52) | HSD17B10POLBAPEX1TDP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |