Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591996 | 0.88 | CA1 (0.54) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL28910541 | 0.87 | MAPT (0.58) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL24590667 | 0.87 | CA1 (0.56) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9777998 | 0.82 | TBXA2R (0.64) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL2840998 | 0.81 | PGR (0.60) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL7566215 | 0.81 | TMPRSS6 (0.48) | CA1CA2 | |
| SCHEMBL9777965 | 0.80 | ALDH1A1 (0.63) | MAPTNPSR1ALDH1A1TBXAS1 | |
| SCHEMBL9777945 | 0.80 | ADRB2 (0.48) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9777989 | 0.79 | TBXA2R (0.49) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9777985 | 0.79 | ADRB2 (0.46) | CA1CA2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |