Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141688 | 0.85 | CCR2 (0.46) | CYP2A6CYP2A13ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL13103802 | 0.82 | POLB (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2375260 | 0.81 | SIGMAR1 (0.46) | ALDH1A1MAPTKDM4EPKMHPGD | |
| SCHEMBL11440371 | 0.80 | HTR7 (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL19623616 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL23328246 | 0.79 | EPHX2 (0.44) | ALDH1A1SMN1; SMN2GAAHPGDHTR7 | |
| SCHEMBL24518600 | 0.78 | SIGMAR1 (0.57) | ALDH1A1MAPTRAB9AKDM4EHPGD | |
| SCHEMBL3229035 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL2377976 | 0.78 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2PKMTDP1 | |
| SCHEMBL12248089 | 0.78 | HTR7 (0.41) | ALDH1A1MAPTSMN1; SMN2PKMHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331983-A2 | Stilbene derivatives, their preparation and their use in medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |
| US-4369310-A | PHOTOGRAPHIC DYES | CIBA-GEIGY LTD. (CH) | 1983-01-18 | — | — | US | disclosed |